Pacylex today announced that data from an investigation of the potential for N-myristoylation inhibition to treat Acute Myeloid Leukemia (AML) will be presented at the American Association for Cancer Research (AACR) Annual Meeting from April 8-13, 2022. This investigation included the association of N-myristoyl transferase (NMT) expression levels with AML patient survival and the in vitro and in vivo demonstration of AML cell killing and tumor reduction with PCLX-001, a proprietary, potent, NMT inhibitor in clinical investigation in Non-Hodgkin’s Lymphoma (NHL) and solid tumor cancer patients.
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